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1

Role of Cytokines in the Pathogenesis of Inflammatory Bowel Disease

Papadakis, Konstantinos A., Targan, Stephan R.

Journal:

Annual Review of Medicine

Year:

2000

Language:

english

File:

PDF, 78 KB

english, 2000

2

Weeding Out the Facts: The Reality About Cannabis and Crohn's Disease

Vu, Michelle P., Melmed, Gil Y., Targan, Stephan R.

Journal:

Clinical Gastroenterology and Hepatology

Year:

2014

Language:

english

File:

PDF, 72 KB

english, 2014

3

Immunomodulator therapy in inflammatory bowel disease

Paul M. Choi, Stephan R. Targan

Journal:

Digestive Diseases and Sciences

Year:

1994

Language:

english

File:

PDF, 917 KB

english, 1994

4

6-thioguanine can cause serious liver injury in inflammatory bowel disease patients

Marla C Dubinsky, Eric A Vasiliauskas, Hardeep Singh, Maria T Abreu, Kostas A Papadakis, Tram Tran, Paul Martin, John M Vierling, Stephen A Geller, Stephan R Targan, Fred F Poordad

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 451 KB

english, 2003

5

ANCA Pattern and LTA haplotype relationship to clinical responses to anti-TNF antibody treatment in crohn's disease

Kent D. Taylor, Scott E. Plevy, Huiying Yang, Carol J. Landers, Mary J. Barry, Jerome I. Rotter, Stephan R. Targan

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 356 KB

english, 2001

6

Molecular Imaging of Murine Intestinal Inflammation With 2-Deoxy-2-[18F]Fluoro-d-Glucose and Positron Emission Tomography

Sarah Brewer, Michael McPherson, Daisuke Fujiwara, Olga Turovskaya, David Ziring, Ling Chen, Hidetoshi Takedatsu, Stephan R. Targan, Bo Wei, Jonathan Braun

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 8.57 MB

english, 2008

7

P034 EFFICACY OF USTEKINUMAB IN CROHN’S DISEASE AT MAINTENENCE WEEK 56: IM-UNITI STUDY

Sandborn, William J., Sands, Bruce E., Colombel, Jean-Frederic, Gasink, Christopher, Patel, Rishit, Jacobstein, Douglas, Gao, Long-long, Ghosh, Subrata, Targan, Stephan, De Villiers, Willem, Hanauer,

Journal:

Gastroenterology

Year:

2019

Language:

english

File:

PDF, 667 KB

english, 2019

8

CD2 mediates activation of the IFN-γ intronic STAT binding region in mucosal T cells

Rivkah Gonsky, Richard L. Deem, Howard A. Young, Stephan R. Targan

Journal:

European Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 322 KB

english, 2003

9

Microbial induction of inflammatory bowel disease associated gene TL1A (TNFSF15) in antigen presenting cells

David Q. Shih, Lola Y. Kwan, Valerie Chavez, Offer Cohavy, Rivkah Gonsky, Elmer Y. Chang, Christopher Chang, Charles O. Elson, Stephan R. Targan

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 1.15 MB

english, 2009

10

TLR8-mediated activation of human monocytes inhibits TL1A expression

Masayuki Saruta, Kathrin S. Michelsen, Lisa S. Thomas, Qi T. Yu, Carol J. Landers, Stephan R. Targan

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 939 KB

english, 2009

11

IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease

Marla C. Dubinsky, Dai Wang, Yoana Picornell, Iwona Wrobel, Lirona Katzir, Antonio Quiros, Debra Dutridge, Ghassan Wahbeh, Gary Silber, Ron Bahar, Emebet Mengesha, Stephan R. Targan, Kent D. Taylor, J

Journal:

Inflammatory Bowel Diseases

Year:

2007

Language:

english

File:

PDF, 83 KB

english, 2007

12

TNFSF15 is an ethnic-specific IBD gene

Yoana Picornell, Ling Mei, Kent Taylor, Huiying Yang, Stephan R. Targan, Jerome I. Rotter

Journal:

Inflammatory Bowel Diseases

Year:

2007

Language:

english

File:

PDF, 129 KB

english, 2007

13

Ex vivo simulation of IgG Fc and T-cell receptor functions: An application to inflammatory bowel disease

Masato Mitsuhashi, Stephan R. Targan

Journal:

Inflammatory Bowel Diseases

Year:

2008

Language:

english

File:

PDF, 214 KB

english, 2008

14

IL23R haplotypes provide a large population attributable risk for Crohn's disease

Kent D. Taylor, Stephan R. Targan, Ling Mei, Andrew F. Ippoliti, Dermot McGovern, Emebet Mengesha, Lily King, Jerome I. Rotter

Journal:

Inflammatory Bowel Diseases

Year:

2008

Language:

english

File:

PDF, 292 KB

english, 2008

15

Enhanced CBir1-specific innate and adaptive immune responses in Crohn's disease

Chong Shen, Carol J. Landers, Carrie Derkowski, Charles O. Elson, Stephan R. Targan

Journal:

Inflammatory Bowel Diseases

Year:

2008

Language:

english

File:

PDF, 402 KB

english, 2008

16

High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in females

Masayuki Saruta, Stephan R. Targan, Ling Mei, Andrew F. Ippoliti, Kent D. Taylor, Jerome I. Rotter

Journal:

Inflammatory Bowel Diseases

Year:

2009

Language:

english

File:

PDF, 281 KB

english, 2009

17

Prospective randomized open-label multicenter phase I/II dose escalation trial of visilizumab (HuM291) in severe steroid-refractory ulcerative colitis

Daniel C. Baumgart, Stephan R. Targan, Axel U. Dignass, Lloyd Mayer, Gert van Assche, Daan W. Hommes, Stephen B. Hanauer, Uma Mahadevan, Walter Reinisch, Scott E. Plevy, Bruce A. Salzberg, Alan L. Buc

Journal:

Inflammatory Bowel Diseases

Year:

2010

Language:

english

File:

PDF, 232 KB

english, 2010

18

Genome wide association (GWA) predictors of anti-TNFα therapeutic responsiveness in pediatric inflammatory bowel disease

Marla C. Dubinsky, Ling Mei, Madison Friedman, Tanvi Dhere, Talin Haritunians, Hakon Hakonarson, Cecilia Kim, Joseph Glessner, Stephan R. Targan, Dermot P. McGovern, Kent D. Taylor, Jerome I. Rotter

Journal:

Inflammatory Bowel Diseases

Year:

2010

Language:

english

File:

PDF, 201 KB

english, 2010

19

Genetic predictors of medically refractory ulcerative colitis

Talin Haritunians, Kent D. Taylor, Stephan R. Targan, Marla Dubinsky, Andrew Ippoliti, Soonil Kwon, Xiuqing Guo, Gil Y. Melmed, Dror Berel, Emebet Mengesha, Bruce M. Psaty, Nicole L. Glazer, Eric A. V

Journal:

Inflammatory Bowel Diseases

Year:

2010

Language:

english

File:

PDF, 426 KB

english, 2010

20

Distinct IFNG methylation in a subset of ulcerative colitis patients based on reactivity to microbial antigens

Rivkah Gonsky, Richard L. Deem, Carol J. Landers, Carrie A. Derkowski, Dror Berel, Dermot P.B. McGovern, Stephan R. Targan

Journal:

Inflammatory Bowel Diseases

Year:

2011

Language:

english

File:

PDF, 156 KB

english, 2011

21

Combination of genetic and quantitative serological immune markers are associated with complicated Crohn's disease behavior

Gary R. Lichtenstein, Stephan R. Targan, Marla C. Dubinsky, Jerome I. Rotter, Derren M. Barken, Fred Princen, Susan Carroll, Michelle Brown, Jordan Stachelski, Emil Chuang, Carol J. Landers, Joanne M.

Journal:

Inflammatory Bowel Diseases

Year:

2011

Language:

english

File:

PDF, 738 KB

english, 2011

22

Anti-tumor necrosis factor-α therapy in Crohn's disease: A magic bullet finally hits its mark

Scott E. Plevy, Stephan R. Targan

Journal:

Inflammatory Bowel Diseases

Year:

1996

Language:

english

File:

PDF, 256 KB

english, 1996

23

The presence of anti-neutrophil antibodies reflects clinical and genetic heterogeneity within inflammatory bowel disease

Jack Satsangi, Carol J. Landers, Ken I. Welsh, Konrad Koss, Stephan Targan, Dr. Derek P. Jewell

Journal:

Inflammatory Bowel Diseases

Year:

1998

Language:

english

File:

PDF, 799 KB

english, 1998

24

The utility of ANCA and ASCA in inflammatory bowel disease

Dr. Stephan R. Targan

Journal:

Inflammatory Bowel Diseases

Year:

1999

Language:

english

File:

PDF, 270 KB

english, 1999

25

A genome-wide search identifies potential new susceptibility loci for Crohn's disease

Yuanhong Ma, Jeffrey D. Ohmen, Zhiming Li, L. Gordon Bentley, Colleen McElree, Sheila Pressman, Stephan R. Targan, Nathan Fischel-Ghodsian, Jerome I. Rotter, Dr. Huiying Yang

Journal:

Inflammatory Bowel Diseases

Year:

1999

Language:

english

File:

PDF, 656 KB

english, 1999

26

Efficacy of mycophenolate mofetil in patients failing 6-mercaptopurine or azathioprine therapy for Crohn's disease

Philip V. Hassard, Eric A. Vasiliauskas, Lori Y. Kam, Stephan R. Targan, Dr. Maria T. Abreu

Journal:

Inflammatory Bowel Diseases

Year:

2000

Language:

english

File:

PDF, 434 KB

english, 2000

27

The role of chemokines and chemokine receptors in mucosal inflammation

Dr. Konstantinos A. Papadakis, Stephan R. Targan

Journal:

Inflammatory Bowel Diseases

Year:

2000

Language:

english

File:

PDF, 1.15 MB

english, 2000

28

Inhibition of cytotoxicity by sulfasalazine. II. Sulfasalazine and sulfapyridine inhibit different stages of the NK and NKCF lytic processes

Fergus Shanahan, Adrene Niederlehner, Richard P. MacDermott, William F. Stenson, Mary G. Kane, Stephan Targan

Journal:

Immunopharmacology

Year:

1986

Language:

english

File:

PDF, 593 KB

english, 1986

29

Enhanced peripheral blood T-cell cytotoxicity in inflammatory bowel disease

Fergus Shanahan, Bernard Leman, Richard Deem, Adrene Niederlehner, Michael Brogan, Stephan Targan

Journal:

Journal of Clinical Immunology

Year:

1989

Language:

english

File:

PDF, 1.05 MB

english, 1989

30

Enhanced neutrophil chemiluminescence in familial mediterranean fever

Peter A. Anton, Stephan R. Targan, Steven R. Vigna, Mark Durham, Arthur D. Schwabe, Fergus Shanahan

Journal:

Journal of Clinical Immunology

Year:

1988

Language:

english

File:

PDF, 1.03 MB

english, 1988

31

Segregation of pANCA antigenic recognition by DNase treatment of neutrophils: Ulcerative colitis, type 1 autoimmune hepatitis, and primary sclerosing cholangitis

Alda Vidrich, Jonathan Lee, Ellin James, Linda Cobb, Stephan Targan

Journal:

Journal of Clinical Immunology

Year:

1995

Language:

english

File:

PDF, 1.46 MB

english, 1995

32

Crohn's disease-associated genetic marker is seen in medically unresponsive ulcerative colitis patients and may be associated with pouch-specific complications

Katherine Facklis, Scott E. Plevy, Eric A. Vasiliauskas, Lori Kam, Kent Taylor, Stephan R. Targan, Phillip R. Fleshner

Journal:

Diseases of the Colon & Rectum

Year:

1999

Language:

english

File:

PDF, 632 KB

english, 1999

33

Serologic Responses in Indeterminate Colitis Patients Before Ileal Pouch-Anal Anastomosis May Determine Those at Risk for Continuous Pouch Inflammation

Thomas Hui, Carol Landers, Eric Vasiliauskas, Maria Abreu, Marla Dubinsky, Konstantinos A. Papadakis, Joanne Price, Ying-Chao Lin, Yang Huiying, Stephan Targan, Phillip Fleshner

Journal:

Diseases of the Colon & Rectum

Year:

2005

Language:

english

File:

PDF, 173 KB

english, 2005

34

Does Infliximab Influence Surgical Morbidity of Ileal Pouch-Anal Anastomosis in Patients with Ulcerative Colitis?

Stefanie J. Schluender, Andrew Ippoliti, Marla Dubinsky, Eric A. Vasiliauskas, Konstantinos A. Papadakis, Ling Mei, Stephan R. Targan, Phillip R. Fleshner

Journal:

Diseases of the Colon & Rectum

Year:

2007

Language:

english

File:

PDF, 294 KB

english, 2007

35

Family History and Serology Predict Crohn’s Disease after Ileal Pouch-Anal Anastomosis for Ulcerative Colitis

Gil Y. Melmed, Phillip R. Fleshner, Ovunc Bardakcioglu, Andrew Ippoliti, Eric A. Vasiliauskas, Konstantinos A. Papadakis, Marla Dubinsky, Carol Landers, Jerome I. Rotter, Stephan R. Targan

Journal:

Diseases of the Colon & Rectum

Year:

2008

Language:

english

File:

PDF, 175 KB

english, 2008

36

TL1A Selectively Enhances IL-12/IL-18-Induced NK Cell Cytotoxicity against NK-Resistant Tumor Targets

Stephanie C. Heidemann, Valerie Chavez, Carol J. Landers, Torsten Kucharzik, John L. Prehn, Stephan R. Targan

Journal:

Journal of Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 640 KB

english, 2010

37

Ex VivoInduction of mRNA in Human Whole Blood as a New Platform of Drug and Dietary Supplement Development

Masato Mitsuhashi, Mieko Ogura, Katsuya Endo, Kazuhiko Obara, Hiroshi Izutsu, Stephan R. Targan, Motoko Maemura, Daisuke Tachikawa, Atsushi Shinagawa

Journal:

Pharmaceutical Research

Year:

2008

Language:

english

File:

PDF, 361 KB

english, 2008

38

Recent advances in IBD pathogenesis: Genetics and immunobiology

David Q. Shih, Stephan R. Targan, Dermot McGovern

Journal:

Current Gastroenterology Reports

Year:

2008

Language:

english

File:

PDF, 395 KB

english, 2008

39

Insights into IBD pathogenesis

David Q. Shih, Stephan R. Targan

Journal:

Current Gastroenterology Reports

Year:

2009

Language:

english

File:

PDF, 426 KB

english, 2009

40

Serologic testing in inflammatory bowel disease: Its value in indeterminate colitis

Konstantinos A. Papadakis, Stephan R. Targan

Journal:

Current Gastroenterology Reports

Year:

1999

Language:

english

File:

PDF, 212 KB

english, 1999

41

Human spontaneous killer cells selective for tumour-derived target cells

JONDAL, MIKAEL, SPINA, CELSA, TARGAN, STEPHAN

Journal:

Year:

1978

File:

PDF, 357 KB

1978

42

Clarifying the causes of Crohn's

Targan, Stephan R., Karp Murphy, Loren

Journal:

Nature Medicine

Year:

1995

File:

PDF, 603 KB

1995

43

Certolizumab pegol

Melmed, Gil Y., Targan, Stephan R., Yasothan, Uma, Hanicq, Delphine, Kirkpatrick, Peter

Journal:

Nature Reviews Drug Discovery

Year:

2008

Language:

english

File:

PDF, 261 KB

english, 2008

44

Infliximab in the treatment of severe, steroid-refractory ulcerative colitis: A pilot study

Dr. Bruce E. Sands, William J. Tremaine, William J. Sandborn, Paul J. Rutgeerts, Stephen B. Hanauer, Lloyd Mayer, Stephan R. Targan, Daniel K. Podolsky

Journal:

Inflammatory Bowel Diseases

Year:

2001

Language:

english

File:

PDF, 165 KB

english, 2001

45

An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy

Dr. Marla C. Dubinsky, Philip V. Hassard, Dr. Ernest G. Seidman, Lori Y. Kam, Maria T. Abreu, Dr. Stephan R. Targan, Eric A. Vasiliauskas

Journal:

Inflammatory Bowel Diseases

Year:

2001

Language:

english

File:

PDF, 272 KB

english, 2001

46

Challenges in IBD research: Updating the scientific agendas

Marjorie Merrick, Charles O. Elson, R. Balfour Sartor, Stephan R. Targan, William J. Sandborn

Journal:

Inflammatory Bowel Diseases

Year:

2003

Language:

english

File:

PDF, 157 KB

english, 2003

47

A pilot study of adalimumab in infliximab-allergic patients

Adrienne Youdim, Eric A. Vasiliauskas, Stephan R. Targan, Konstantinos A. Papadakis, Andrew Ippoliti, Marla C. Dubinsky, Juan Lechago, Jane Paavola, Jaime Loane, Susie K. Lee, Joanne Gaiennie, Katie S

Journal:

Inflammatory Bowel Diseases

Year:

2004

Language:

english

File:

PDF, 535 KB

english, 2004

48

The spectrum of gastrointestinal toxicity and effect on disease activity of selective cyclooxygenase-2 inhibitors in patients with inflammatory bowel disease

Robin Matuk, Jonathan Crawford, Maria T. Abreu, Stephan R. Targan, Eric A. Vasiliauskas, Konstantinos A. Papadakis

Journal:

Inflammatory Bowel Diseases

Year:

2004

Language:

english

File:

PDF, 114 KB

english, 2004

49

Expression and regulation of the chemokine receptor CXCR3 on lymphocytes from normal and inflammatory bowel disease mucosa

Konstantinos A. Papadakis, John Prehn, Daocheng Zhu, Carol Landers, Joanne Gaiennie, Phillip R. Fleshner, Stephan R. Targan

Journal:

Inflammatory Bowel Diseases

Year:

2004

Language:

english

File:

PDF, 1004 KB

english, 2004

50

State of the art: IBD therapy and clinical trials in IBD

Kim L Isaacs, James D Lewis, William J Sandborn, Bruce E Sands, Stephan R Targan

Journal:

Inflammatory Bowel Diseases

Year:

2005

Language:

english

File:

PDF, 422 KB

english, 2005